There is a lot of discussion about MTHFR (methyl tetrahydrofolate reductase) gene and methylation and its impact on human health. However, most people are still unaware about methylation and its role in ensuring normal functioning of the human body. Understanding methylation will help in connecting the dots between our genes, food and the reason why some people experience a variety of methylation-related health issues while others don't. Methylation is currently one of the hottest areas in life sciences. It has wide-ranging and powerful effects on many aspects of health, with immense potential in medicine.