"Latinx" (pronounced "La-teen-ex") is the gender-neutral term that covers the largest racial minority in the United States, and the poorest but fastest-growing American group, whose political empowerment is altering the balance of forces in a growing number of states. In this groundbreaking discussion, Ed Morales explains how Latinx political identities are tied to a long Latin American history of mestizaje, translatable as "mixedness" or "hybridity", and that this border thinking is both a key to understanding Latinx cultures and a challenge to America's infamously black-white racial regime.