In Taisho-era Japan, kindhearted Tanjiro Kamado makes a living selling charcoal. But his peaceful life is shattered when a demon slaughters his entire family. His little sister Nezuko is the only survivor, but she has been transformed into a demon herself! Tanjiro sets out on a dangerous journey to find a way to return his sister to normal and destroy the demon who ruined his life.

The fight with Kokushibo, the highest-ranking demon among Muzan's servants, is over. Although Himejima and Sanemi defeated Kokushibo and sent him to hell, the price the Demon Slayer Corps has paid is very high. Kiriya Ubuyashiki, the new leader of the Demon Slayers, struggles to recover from the losses. With the battle against Muzan far from over, the remaining fighters will need his help more than ever. Meanwhile, deep within Infinity Castle, Tanjiro and his friends come face-to-face with their nemesis at last...