Using insights from the disciplines of biblical studies and missiology, this study explores the extent to which cross-cultural insights can be drawn from Luke's story of Christianity as it moves from the particular (the Jews) to the universal (Jew and Gentile). Luke's narrative, while cast in religious categories, contains numerous implications on the cross-cultural nature of the messianic movement because the terms he uses have sociological dimensions. The study's conclusions should interest both New Testament scholars and missiologists.